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PAR-dependent and geometry-dependent mechanisms of spindle positioning

During intrinsically asymmetric division, the spindle is oriented onto a polarized axis specified by a group of conserved PAR proteins. Extrinsic geometric asymmetry generated by cell shape also affects spindle orientation in some systems, but how intrinsic and extrinsic mechanisms coexist without i...

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Detalles Bibliográficos
Autores principales: Tsou, Meng-Fu Bryan, Ku, Wei, Hayashi, Adam, Rose, Lesilee S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173762/
https://www.ncbi.nlm.nih.gov/pubmed/12642612
http://dx.doi.org/10.1083/jcb.200209079