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Association of diacylglycerol kinase ζ with protein kinase C α: spatial regulation of diacylglycerol signaling
Activation of PKC depends on the availability of DAG, a signaling lipid that is tightly and dynamically regulated. DAG kinase (DGK) terminates DAG signaling by converting it to phosphatidic acid. Here, we demonstrate that DGKζ inhibits PKCα activity and that DGK activity is required for this inhibit...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173768/ https://www.ncbi.nlm.nih.gov/pubmed/12629049 http://dx.doi.org/10.1083/jcb.200208120 |