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A neurotoxic peripherin splice variant in a mouse model of ALS
Peripherin, a neuronal intermediate filament (nIF) protein found associated with pathological aggregates in motor neurons of patients with amyotrophic lateral sclerosis (ALS) and of transgenic mice overexpressing mutant superoxide dismutase-1 (SOD1(G37R)), induces the selective degeneration of motor...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173778/ https://www.ncbi.nlm.nih.gov/pubmed/12642616 http://dx.doi.org/10.1083/jcb.200205027 |