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A neurotoxic peripherin splice variant in a mouse model of ALS

Peripherin, a neuronal intermediate filament (nIF) protein found associated with pathological aggregates in motor neurons of patients with amyotrophic lateral sclerosis (ALS) and of transgenic mice overexpressing mutant superoxide dismutase-1 (SOD1(G37R)), induces the selective degeneration of motor...

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Detalles Bibliográficos
Autores principales: Robertson, Janice, Doroudchi, Mohammad M., Nguyen, Minh Dang, Durham, Heather D., Strong, Michael J., Shaw, Gerry, Julien, Jean-Pierre, Mushynski, Walter E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173778/
https://www.ncbi.nlm.nih.gov/pubmed/12642616
http://dx.doi.org/10.1083/jcb.200205027