Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

Centromere-associated protein-E (CENP-E) is an essential mitotic kinesin that is required for efficient, stable microtubule capture at kinetochores. It also directly binds to BubR1, a kinetochore-associated kinase implicated in the mitotic checkpoint, the major cell cycle control pathway in which un...

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Detalles Bibliográficos
Autores principales: Weaver, Beth A.A., Bonday, Zahid Q., Putkey, Frances R., Kops, Geert J.P.L., Silk, Alain D., Cleveland, Don W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173788/
https://www.ncbi.nlm.nih.gov/pubmed/12925705
http://dx.doi.org/10.1083/jcb.200303167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173788/
https://www.ncbi.nlm.nih.gov/pubmed/12925705
http://dx.doi.org/10.1083/jcb.200303167

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