Phosphoinositide 3-kinase regulates β2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/β-arrestin complex

Internalization of β-adrenergic receptors (βARs) occurs by the sequential binding of β-arrestin, the clathrin adaptor AP-2, and clathrin. D-3 phosphoinositides, generated by the action of phosphoinositide 3-kinase (PI3K) may regulate the endocytic process; however, the precise molecular mechanism is...

Descripción completa

Detalles Bibliográficos
Autores principales: Naga Prasad, Sathyamangla V., Laporte, Stéphane A., Chamberlain, Dean, Caron, Marc G., Barak, Larry, Rockman, Howard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173831/
https://www.ncbi.nlm.nih.gov/pubmed/12163475
http://dx.doi.org/10.1083/jcb.200202113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173831/
https://www.ncbi.nlm.nih.gov/pubmed/12163475
http://dx.doi.org/10.1083/jcb.200202113

Ejemplares similares