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Endostatin is a potential inhibitor of Wnt signaling

Endostatin (ES) is a fragment of collagen XVIII that possesses antiangiogenic activity. To gain insight into ES-mediated signaling, we studied the effects of ES RNA on Xenopus embryogenesis and observed developmental abnormalities consistent with impaired Wnt signaling. ES RNA blocked the axis dupli...

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Detalles Bibliográficos
Autores principales: Hanai, Jun-ichi, Gloy, Joachim, Karumanchi, S. Ananth, Kale, Sujata, Tang, Jian, Hu, Guang, Chan, Barden, Ramchandran, Ramani, Jha, Vivek, Sukhatme, Vikas P., Sokol, Sergei
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173844/
https://www.ncbi.nlm.nih.gov/pubmed/12147676
http://dx.doi.org/10.1083/jcb.200203064