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Endostatin is a potential inhibitor of Wnt signaling
Endostatin (ES) is a fragment of collagen XVIII that possesses antiangiogenic activity. To gain insight into ES-mediated signaling, we studied the effects of ES RNA on Xenopus embryogenesis and observed developmental abnormalities consistent with impaired Wnt signaling. ES RNA blocked the axis dupli...
Autores principales: | Hanai, Jun-ichi, Gloy, Joachim, Karumanchi, S. Ananth, Kale, Sujata, Tang, Jian, Hu, Guang, Chan, Barden, Ramchandran, Ramani, Jha, Vivek, Sukhatme, Vikas P., Sokol, Sergei |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173844/ https://www.ncbi.nlm.nih.gov/pubmed/12147676 http://dx.doi.org/10.1083/jcb.200203064 |
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