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Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland

To develop an inducible and progressive model of mammary gland tumorigenesis, transgenic mice were generated with a mouse mammary tumor virus–long terminal repeat–driven, conditional, fibroblast growth factor (FGF)–independent FGF receptor (FGFR)1 (iFGFR1) that can be induced to dimerize with the dr...

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Detalles Bibliográficos
Autores principales: Welm, Bryan E., Freeman, Kevin W., Chen, Mercy, Contreras, Alejandro, Spencer, David M., Rosen, Jeffrey M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173854/
https://www.ncbi.nlm.nih.gov/pubmed/12011115
http://dx.doi.org/10.1083/jcb.200107119