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Meiotic spindle stability depends on MAPK-interacting and spindle-stabilizing protein (MISS), a new MAPK substrate

Vertebrate oocytes arrest in the second metaphase of meiosis (metaphase II [MII]) by an activity called cytostatic factor (CSF), with aligned chromosomes and stable spindles. Segregation of chromosomes occurs after fertilization. The Mos/…/MAPK (mitogen-activated protein kinases) pathway mediates th...

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Detalles Bibliográficos
Autores principales: Lefebvre, Christophe, Terret, M. Emilie, Djiane, Alexandre, Rassinier, Pascale, Maro, Bernard, Verlhac, Marie-Hélène
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173866/
https://www.ncbi.nlm.nih.gov/pubmed/12011110
http://dx.doi.org/10.1083/jcb.200202052