CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo

BACKGROUND: Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9). This leads in particular to the expression of proinflammatory mediators such as tumor necrosis factor (...

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Detalles Bibliográficos
Autores principales: Knuefermann, Pascal, Baumgarten, Georg, Koch, Alexander, Schwederski, Markus, Velten, Markus, Ehrentraut, Heidi, Mersmann, Jan, Meyer, Rainer, Hoeft, Andreas, Zacharowski, Kai, Grohé, Christian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173891/
https://www.ncbi.nlm.nih.gov/pubmed/17925007
http://dx.doi.org/10.1186/1465-9921-8-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173891/
https://www.ncbi.nlm.nih.gov/pubmed/17925007
http://dx.doi.org/10.1186/1465-9921-8-72

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