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Enhancing the anti-angiogenic action of histone deacetylase inhibitors

BACKGROUND: Histone deacetylase inhibitors (HDACIs) have many effects on cancer cells, such as growth inhibition, induction of cell death, differentiation, and anti-angiogenesis, all with a wide therapeutic index. However, clinical trials demonstrate that HDACIs are more likely to be effective when...

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Detalles Bibliográficos
Autores principales: Kuljaca, Selena, Liu, Tao, Tee, Andrew EL, Haber, Michelle, Norris, Murray D, Dwarte, Tanya, Marshall, Glenn M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173905/
https://www.ncbi.nlm.nih.gov/pubmed/17958916
http://dx.doi.org/10.1186/1476-4598-6-68