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Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo
Skeletal mass is maintained by a balance between formation and resorption, cell proliferation and apoptosis. In vitro, glucocorticoids (GCs) decrease extracellular signal-regulated kinases (ERK) activation by mitogens, thus inhibiting osteoblast proliferation. Both ERK activity and proliferation are...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for Endocrinology
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173947/ https://www.ncbi.nlm.nih.gov/pubmed/17951534 http://dx.doi.org/10.1677/JOE-07-0217 |