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Compartmentalization of integrin α6β4 signaling in lipid rafts

Integrin α6β4 signaling proceeds through Src family kinase (SFK)–mediated phosphorylation of the cytoplasmic tail of β4, recruitment of Shc, and activation of Ras and phosphoinositide-3 kinase. Upon cessation of signaling, α6β4 mediates assembly of hemidesmosomes. Here, we report that part of α6β4 i...

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Detalles Bibliográficos
Autores principales: Gagnoux-Palacios, Laurent, Dans, Michael, van't Hof, Wouter, Mariotti, Agnese, Pepe, Angela, Meneguzzi, Guerrino, Resh, Marilyn D., Giancotti, Filippo G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173954/
https://www.ncbi.nlm.nih.gov/pubmed/14517202
http://dx.doi.org/10.1083/jcb.200305006