A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation

The mammalian nuclear lamina protein lamin B1 is posttranslationally modified by farnesylation, endoproteolysis, and carboxymethylation at a carboxyl-terminal CAAX motif. In this work, we demonstrate that the CAAX endoprotease Rce1 is required for lamin B1 endoproteolysis, demonstrate an independent...

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Detalles Bibliográficos
Autores principales: Maske, Christopher P., Hollinshead, Michael S., Higbee, Niall C., Bergo, Martin O., Young, Stephen G., Vaux, David J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173957/
https://www.ncbi.nlm.nih.gov/pubmed/14504265
http://dx.doi.org/10.1083/jcb.200303113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173957/
https://www.ncbi.nlm.nih.gov/pubmed/14504265
http://dx.doi.org/10.1083/jcb.200303113

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