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A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation
The mammalian nuclear lamina protein lamin B1 is posttranslationally modified by farnesylation, endoproteolysis, and carboxymethylation at a carboxyl-terminal CAAX motif. In this work, we demonstrate that the CAAX endoprotease Rce1 is required for lamin B1 endoproteolysis, demonstrate an independent...
Autores principales: | Maske, Christopher P., Hollinshead, Michael S., Higbee, Niall C., Bergo, Martin O., Young, Stephen G., Vaux, David J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173957/ https://www.ncbi.nlm.nih.gov/pubmed/14504265 http://dx.doi.org/10.1083/jcb.200303113 |
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