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Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing

The nuclear structures that contain symmetrical dimethylated arginine (sDMA)–modified proteins and the role of this posttranslational modification is unknown. Here we report that the Cajal body is a major epitope in HeLa cells for an sDMA-specific antibody and that coilin is an sDMA-containing prote...

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Detalles Bibliográficos
Autores principales: Boisvert, François-Michel, Côté, Jocelyn, Boulanger, Marie-Chloé, Cléroux, Patrick, Bachand, François, Autexier, Chantal, Richard, Stéphane
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173973/
https://www.ncbi.nlm.nih.gov/pubmed/12486110
http://dx.doi.org/10.1083/jcb.200207028