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Concentrative sorting of secretory cargo proteins into COPII-coated vesicles

Here, we show that efficient transport of membrane and secretory proteins from the ER of Saccharomyces cerevisiae requires concentrative and signal-mediated sorting. Three independent markers of bulk flow transport out of the ER indicate that in the absence of an ER export signal, molecules are inef...

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Detalles Bibliográficos
Autores principales: Malkus, Per, Jiang, Feng, Schekman, Randy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173974/
https://www.ncbi.nlm.nih.gov/pubmed/12499351
http://dx.doi.org/10.1083/jcb.200208074