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Concentrative sorting of secretory cargo proteins into COPII-coated vesicles
Here, we show that efficient transport of membrane and secretory proteins from the ER of Saccharomyces cerevisiae requires concentrative and signal-mediated sorting. Three independent markers of bulk flow transport out of the ER indicate that in the absence of an ER export signal, molecules are inef...
Autores principales: | Malkus, Per, Jiang, Feng, Schekman, Randy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173974/ https://www.ncbi.nlm.nih.gov/pubmed/12499351 http://dx.doi.org/10.1083/jcb.200208074 |
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