Cargando…

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1

Directed cell movement is a multi-step process requiring an initial spatial polarization that is established by asymmetric stimulation of Rho GTPases, phosphoinositides (PIs), and actin polymerization. We report that the Na-H exchanger isoform 1 (NHE1), a ubiquitously expressed plasma membrane ion e...

Descripción completa

Detalles Bibliográficos
Autores principales: Denker, Sheryl P., Barber, Diane L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173980/
https://www.ncbi.nlm.nih.gov/pubmed/12486114
http://dx.doi.org/10.1083/jcb.200208050