Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes

Phospholipase D (PLD) generates lipid signals that coordinate membrane trafficking with cellular signaling. PLD activity in vitro and in vivo is dependent on phosphoinositides with a vicinal 4,5-phosphate pair. Yeast and mammalian PLDs contain an NH(2)-terminal pleckstrin homology (PH) domain that h...

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Detalles Bibliográficos
Autores principales: Sciorra, Vicki A., Rudge, Simon A., Wang, Jiyao, McLaughlin, Stuart, Engebrecht, JoAnne, Morris, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173982/
https://www.ncbi.nlm.nih.gov/pubmed/12486109
http://dx.doi.org/10.1083/jcb.200205056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173982/
https://www.ncbi.nlm.nih.gov/pubmed/12486109
http://dx.doi.org/10.1083/jcb.200205056

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