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The Cdc37 protein kinase–binding domain is sufficient for protein kinase activity and cell viability

Cdc37 is a molecular chaperone required for folding of protein kinases. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. Using a genetic approach with Saccharomyces cerevisiae, we s...

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Detalles Bibliográficos
Autores principales: Lee, Paul, Rao, Jie, Fliss, Albert, Yang, Emy, Garrett, Stephen, Caplan, Avrom J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173992/
https://www.ncbi.nlm.nih.gov/pubmed/12499358
http://dx.doi.org/10.1083/jcb.200210121