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The Cdc37 protein kinase–binding domain is sufficient for protein kinase activity and cell viability
Cdc37 is a molecular chaperone required for folding of protein kinases. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. Using a genetic approach with Saccharomyces cerevisiae, we s...
Autores principales: | Lee, Paul, Rao, Jie, Fliss, Albert, Yang, Emy, Garrett, Stephen, Caplan, Avrom J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173992/ https://www.ncbi.nlm.nih.gov/pubmed/12499358 http://dx.doi.org/10.1083/jcb.200210121 |
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