FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest

Unregulated FGF signaling affects endochondral ossification and long bone growth, causing several genetic forms of human dwarfism. One major mechanism by which FGFs regulate endochondral bone growth is through their inhibitory effect on chondrocyte proliferation. Because mice with targeted mutations...

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Detalles Bibliográficos
Autores principales: Laplantine, Emmanuel, Rossi, Ferdinand, Sahni, Malika, Basilico, Claudio, Cobrinik, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174007/
https://www.ncbi.nlm.nih.gov/pubmed/12177046
http://dx.doi.org/10.1083/jcb.200205025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174007/
https://www.ncbi.nlm.nih.gov/pubmed/12177046
http://dx.doi.org/10.1083/jcb.200205025

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