Survival of, and competition between, oligodendrocytes expressing different alleles of the Plp gene

Mutations in the X-linked Plp gene lead to dysmyelinating phenotypes and oligodendrocyte cell death. Here, we exploit the X inactivation phenomenon to show that a hierarchy exists in the influence of different mutant Plp alleles on oligodendrocyte survival. We used compound heterozygote mice to stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Edgar, J.M., Anderson, T.J., Dickinson, P.J., Barrie, J.A., McCulloch, M.C., Nave, K.-A., Griffiths, I.R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174021/
https://www.ncbi.nlm.nih.gov/pubmed/12177040
http://dx.doi.org/10.1083/jcb.200202124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174021/
https://www.ncbi.nlm.nih.gov/pubmed/12177040
http://dx.doi.org/10.1083/jcb.200202124

Ejemplares similares