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Survival of, and competition between, oligodendrocytes expressing different alleles of the Plp gene
Mutations in the X-linked Plp gene lead to dysmyelinating phenotypes and oligodendrocyte cell death. Here, we exploit the X inactivation phenomenon to show that a hierarchy exists in the influence of different mutant Plp alleles on oligodendrocyte survival. We used compound heterozygote mice to stud...
Autores principales: | Edgar, J.M., Anderson, T.J., Dickinson, P.J., Barrie, J.A., McCulloch, M.C., Nave, K.-A., Griffiths, I.R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174021/ https://www.ncbi.nlm.nih.gov/pubmed/12177040 http://dx.doi.org/10.1083/jcb.200202124 |
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