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Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus

Glycoprotein fucosylation enables fringe-dependent modulation of signal transduction by Notch transmembrane receptors, contributes to selectin-dependent leukocyte trafficking, and is faulty in leukocyte adhesion deficiency (LAD) type II, also known as congenital disorder of glycosylation (CDG)-IIc,...

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Detalles Bibliográficos
Autores principales: Smith, Peter L., Myers, Jay T., Rogers, Clare E., Zhou, Lan, Petryniak, Bronia, Becker, Daniel J., Homeister, Jonathon W., Lowe, John B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174027/
https://www.ncbi.nlm.nih.gov/pubmed/12186857
http://dx.doi.org/10.1083/jcb.200203125