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Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus
Glycoprotein fucosylation enables fringe-dependent modulation of signal transduction by Notch transmembrane receptors, contributes to selectin-dependent leukocyte trafficking, and is faulty in leukocyte adhesion deficiency (LAD) type II, also known as congenital disorder of glycosylation (CDG)-IIc,...
Autores principales: | Smith, Peter L., Myers, Jay T., Rogers, Clare E., Zhou, Lan, Petryniak, Bronia, Becker, Daniel J., Homeister, Jonathon W., Lowe, John B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174027/ https://www.ncbi.nlm.nih.gov/pubmed/12186857 http://dx.doi.org/10.1083/jcb.200203125 |
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