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Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow

Leukocytes roll on selectins at nearly constant velocities over a wide range of wall shear stresses. Ligand-coupled microspheres roll faster on selectins and detach quickly as wall shear stress is increased. To examine whether the superior performance of leukocytes reflects molecular features of nat...

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Detalles Bibliográficos
Autores principales: Yago, Tadayuki, Leppänen, Anne, Qiu, Haiying, Marcus, Warren D., Nollert, Matthias U., Zhu, Cheng, Cummings, Richard D., McEver, Rodger P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174028/
https://www.ncbi.nlm.nih.gov/pubmed/12177042
http://dx.doi.org/10.1083/jcb.200204041