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Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms

The adapter protein tumor necrosis factor receptor (TNFR)1–associated death domain (TRADD) plays an essential role in recruiting signaling molecules to the TNFRI receptor complex at the cell membrane. Here we show that TRADD contains a nuclear export and import sequence that allow shuttling between...

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Detalles Bibliográficos
Autores principales: Morgan, Michael, Thorburn, Jacqueline, Pandolfi, Pier Paolo, Thorburn, Andrew
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174032/
https://www.ncbi.nlm.nih.gov/pubmed/12045187
http://dx.doi.org/10.1083/jcb.200204039