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Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms
The adapter protein tumor necrosis factor receptor (TNFR)1–associated death domain (TRADD) plays an essential role in recruiting signaling molecules to the TNFRI receptor complex at the cell membrane. Here we show that TRADD contains a nuclear export and import sequence that allow shuttling between...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174032/ https://www.ncbi.nlm.nih.gov/pubmed/12045187 http://dx.doi.org/10.1083/jcb.200204039 |