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SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

The Arp2/3 complex and its activators, Scar/WAVE and Wiskott-Aldrich Syndrome protein (WASp), promote actin polymerization in vitro and have been proposed to influence cell shape and motility in vivo. We demonstrate that the Drosophila Scar homologue, SCAR, localizes to actin-rich structures and is...

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Detalles Bibliográficos
Autores principales: Zallen, Jennifer A., Cohen, Yehudit, Hudson, Andrew M., Cooley, Lynn, Wieschaus, Eric, Schejter, Eyal D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174092/
https://www.ncbi.nlm.nih.gov/pubmed/11854309
http://dx.doi.org/10.1083/jcb.200109057