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Mg(2+) Enhances Voltage Sensor/Gate Coupling in BK Channels
BK (Slo1) potassium channels are activated by millimolar intracellular Mg(2+) as well as micromolar Ca(2+) and membrane depolarization. Mg(2+) and Ca(2+) act in an approximately additive manner at different binding sites to shift the conductance–voltage (G(K)-V) relation, suggesting that these ligan...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174156/ https://www.ncbi.nlm.nih.gov/pubmed/18166624 http://dx.doi.org/10.1085/jgp.200709877 |