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Sulfonylurea Receptors Type 1 and 2A Randomly Assemble to Form Heteromeric K(ATP) Channels of Mixed Subunit Composition

ATP-sensitive potassium (K(ATP)) channels play important roles in regulating insulin secretion, controlling vascular tone, and protecting cells against metabolic stresses. K(ATP) channels are heterooctamers of four pore-forming inwardly rectifying (Kir6.2) subunits and four sulfonylurea receptor (SU...

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Detalles Bibliográficos
Autores principales: Chan, Kim W., Wheeler, Adam, Csanády, László
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174157/
https://www.ncbi.nlm.nih.gov/pubmed/18079561
http://dx.doi.org/10.1085/jgp.200709894