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Sulfonylurea Receptors Type 1 and 2A Randomly Assemble to Form Heteromeric K(ATP) Channels of Mixed Subunit Composition
ATP-sensitive potassium (K(ATP)) channels play important roles in regulating insulin secretion, controlling vascular tone, and protecting cells against metabolic stresses. K(ATP) channels are heterooctamers of four pore-forming inwardly rectifying (Kir6.2) subunits and four sulfonylurea receptor (SU...
Autores principales: | Chan, Kim W., Wheeler, Adam, Csanády, László |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174157/ https://www.ncbi.nlm.nih.gov/pubmed/18079561 http://dx.doi.org/10.1085/jgp.200709894 |
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