Cargando…

Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End

The multisubunit protein, dynactin, is a critical component of the cytoplasmic dynein motor machinery. Dynactin contains two distinct structural domains: a projecting sidearm that interacts with dynein and an actin-like minifilament backbone that is thought to bind cargo. Here, we use biochemical, u...

Descripción completa

Detalles Bibliográficos
Autores principales: Eckley, D. Mark, Gill, Steven R., Melkonian, Karin A., Bingham, James B., Goodson, Holly V., Heuser, John E., Schroer, Trina A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174220/
https://www.ncbi.nlm.nih.gov/pubmed/10525537