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Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End
The multisubunit protein, dynactin, is a critical component of the cytoplasmic dynein motor machinery. Dynactin contains two distinct structural domains: a projecting sidearm that interacts with dynein and an actin-like minifilament backbone that is thought to bind cargo. Here, we use biochemical, u...
Autores principales: | Eckley, D. Mark, Gill, Steven R., Melkonian, Karin A., Bingham, James B., Goodson, Holly V., Heuser, John E., Schroer, Trina A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174220/ https://www.ncbi.nlm.nih.gov/pubmed/10525537 |
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