The Kinesin-Related Protein, Hset, Opposes the Activity of Eg5 and Cross-Links Microtubules in the Mammalian Mitotic Spindle

We have prepared antibodies specific for HSET, the human homologue of the KAR3 family of minus end-directed motors. Immuno-EM with these antibodies indicates that HSET frequently localizes between microtubules within the mammalian metaphase spindle consistent with a microtubule cross-linking functio...

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Detalles Bibliográficos
Autores principales: Mountain, Vicki, Simerly, Calvin, Howard, Louisa, Ando, Asako, Schatten, Gerald, Compton, Duane A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174226/
https://www.ncbi.nlm.nih.gov/pubmed/10525540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174226/
https://www.ncbi.nlm.nih.gov/pubmed/10525540

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