Integrin-Associated Protein Stimulates α2β1-Dependent Chemotaxis via GI-Mediated Inhibition of Adenylate Cyclase and Extracellular-Regulated Kinases

Integrin-associated protein (IAP/CD47) augments the function of α2β1 integrin in smooth muscle cells (SMC), resulting in enhanced chemotaxis toward soluble collagen (Wang, X-Q., and W.A. Frazier. 1998. Mol. Biol. Cell. 9:865). IAP-deficient SMC derived from IAP(−/−) animals did not migrate in respon...

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Detalles Bibliográficos
Autores principales: Wang, Xue-Qing, Lindberg, Frederik P., Frazier, William A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174227/
https://www.ncbi.nlm.nih.gov/pubmed/10525543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174227/
https://www.ncbi.nlm.nih.gov/pubmed/10525543

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