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Dynactin Is Required for Microtubule Anchoring at Centrosomes

The multiprotein complex, dynactin, is an integral part of the cytoplasmic dynein motor and is required for dynein-based motility in vitro and in vivo. In living cells, perturbation of the dynein–dynactin interaction profoundly blocks mitotic spindle assembly, and inhibition or depletion of dynein o...

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Detalles Bibliográficos
Autores principales: Quintyne, N.J., Gill, S.R., Eckley, D.M., Crego, C.L., Compton, D.A., Schroer, T.A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174233/
https://www.ncbi.nlm.nih.gov/pubmed/10525538