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Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts

To examine the role of mitogen-activated protein kinase and nuclear factor kappa B (NF-κB) pathways on osteoclast survival and activation, we constructed adenovirus vectors carrying various mutants of signaling molecules: dominant negative Ras (Ras(DN)), constitutively active MEK1 (MEK(CA)), dominan...

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Detalles Bibliográficos
Autores principales: Miyazaki, Tsuyoshi, Katagiri, Hideki, Kanegae, Yumi, Takayanagi, Hiroshi, Sawada, Yasuhiro, Yamamoto, Aiichiro, Pando, Mattew P., Asano, Tomoichiro, Verma, Inder M., Oda, Hiromi, Nakamura, Kozo, Tanaka, Sakae
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174281/
https://www.ncbi.nlm.nih.gov/pubmed/10648566