Active Caspases and Cleaved Cytokeratins Are Sequestered into Cytoplasmic Inclusions in Trail-Induced Apoptosis

Tumor necrosis factor–related apoptosis- inducing ligand (TRAIL) –induced apoptosis, in transformed human breast epithelial MCF-7 cells, resulted in a time-dependent activation of the initiator caspases-8 and -9 and the effector caspase-7. Cleavage of caspase-8 and its preferred substrate, Bid, prec...

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Detalles Bibliográficos
Autores principales: MacFarlane, Marion, Merrison, Wendy, Dinsdale, David, Cohen, Gerald M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174305/
https://www.ncbi.nlm.nih.gov/pubmed/10725337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174305/
https://www.ncbi.nlm.nih.gov/pubmed/10725337

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