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Conformational Requirements for Glycoprotein Reglucosylation in the Endoplasmic Reticulum

Newly synthesized glycoproteins interact during folding and quality control in the ER with calnexin and calreticulin, two lectins specific for monoglucosylated oligosaccharides. Binding and release are regulated by two enzymes, glucosidase II and UDP-Glc:glycoprotein:glycosyltransferase (GT), which...

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Detalles Bibliográficos
Autores principales: Trombetta, E. Sergio, Helenius, Ari
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174309/
https://www.ncbi.nlm.nih.gov/pubmed/10725325