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Phosphorylation of Adf/Cofilin Abolishes Egf-Induced Actin Nucleation at the Leading Edge and Subsequent Lamellipod Extension

In metastatic rat mammary adenocarcinoma cells, cell motility can be induced by epidermal growth factor. One of the early events in this process is the massive generation of actin barbed ends, which elongate to form filaments immediately adjacent to the plasma membrane at the tip of the leading edge...

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Detalles Bibliográficos
Autores principales: Zebda, Noureddine, Bernard, Ora, Bailly, Maryse, Welti, Susan, Lawrence, David S., Condeelis, John S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174362/
https://www.ncbi.nlm.nih.gov/pubmed/11086013