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Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines

BACKGROUND: Despite numerous studies aimed at verifying the antitumor activity of nitric oxide-releasing nonsteroidal antiflammatory drugs (NO-NSAIDs), little is known about the molecular targets responsible for their antineoplastic properties. In the present study, we investigated the mechanisms un...

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Detalles Bibliográficos
Autores principales: Tesei, Anna, Rosetti, Marco, Ulivi, Paola, Fabbri, Francesco, Medri, Laura, Vannini, Ivan, Bolla, Manlio, Amadori, Dino, Zoli, Wainer
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174440/
https://www.ncbi.nlm.nih.gov/pubmed/17971198
http://dx.doi.org/10.1186/1479-5876-5-52