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Recurrent adenylation domain replacement in the microcystin synthetase gene cluster

BACKGROUND: Microcystins are small cyclic heptapeptide toxins produced by a range of distantly related cyanobacteria. Microcystins are synthesized on large NRPS-PKS enzyme complexes. Many structural variants of microcystins are produced simulatenously. A recombination event between the first module...

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Detalles Bibliográficos
Autores principales: Fewer, David P, Rouhiainen, Leo, Jokela, Jouni, Wahlsten, Matti, Laakso, Kati, Wang, Hao, Sivonen, Kaarina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174460/
https://www.ncbi.nlm.nih.gov/pubmed/17908306
http://dx.doi.org/10.1186/1471-2148-7-183