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Recurrent adenylation domain replacement in the microcystin synthetase gene cluster
BACKGROUND: Microcystins are small cyclic heptapeptide toxins produced by a range of distantly related cyanobacteria. Microcystins are synthesized on large NRPS-PKS enzyme complexes. Many structural variants of microcystins are produced simulatenously. A recombination event between the first module...
Autores principales: | Fewer, David P, Rouhiainen, Leo, Jokela, Jouni, Wahlsten, Matti, Laakso, Kati, Wang, Hao, Sivonen, Kaarina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174460/ https://www.ncbi.nlm.nih.gov/pubmed/17908306 http://dx.doi.org/10.1186/1471-2148-7-183 |
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