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Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides
BACKGROUND: A right-handed, calcium-dependent β-roll structure found in secreted proteases and repeat-in-toxin proteins was used as a template for the design of minimal, soluble, monomeric polypeptides that would fold in the presence of Ca(2+). Two polypeptides were synthesised to contain two and fo...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174480/ https://www.ncbi.nlm.nih.gov/pubmed/17908326 http://dx.doi.org/10.1186/1472-6807-7-63 |