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Antibody-protein interactions: benchmark datasets and prediction tools evaluation

BACKGROUND: The ability to predict antibody binding sites (aka antigenic determinants or B-cell epitopes) for a given protein is a precursor to new vaccine design and diagnostics. Among the various methods of B-cell epitope identification X-ray crystallography is one of the most reliable methods. Us...

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Detalles Bibliográficos
Autores principales: Ponomarenko, Julia V, Bourne, Philip E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174481/
https://www.ncbi.nlm.nih.gov/pubmed/17910770
http://dx.doi.org/10.1186/1472-6807-7-64