Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules

BACKGROUND: cis-Regulatory modules (CRMs) of eukaryotic genes often contain multiple binding sites for transcription factors. The phenomenon that binding sites form clusters in CRMs is exploited in many algorithms to locate CRMs in a genome. This gives rise to the problem of calculating the statisti...

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Detalles Bibliográficos
Autores principales: Boeva, Valentina, Clément, Julien, Régnier, Mireille, Roytberg, Mikhail A, Makeev, Vsevolod J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174486/
https://www.ncbi.nlm.nih.gov/pubmed/17927813
http://dx.doi.org/10.1186/1748-7188-2-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174486/
https://www.ncbi.nlm.nih.gov/pubmed/17927813
http://dx.doi.org/10.1186/1748-7188-2-13

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