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Y-Chromosome Based Evidence for Pre-Neolithic Origin of the Genetically Homogeneous but Diverse Sardinian Population: Inference for Association Scans

The island of Sardinia shows a unique high incidence of several autoimmune diseases with multifactorial inheritance, particularly type 1 diabetes and multiple sclerosis. The prior knowledge of the genetic structure of this population is fundamental to establish the optimal design for association stu...

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Detalles Bibliográficos
Autores principales: Contu, Daniela, Morelli, Laura, Santoni, Federico, Foster, Jamie W., Francalacci, Paolo, Cucca, Francesco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174525/
https://www.ncbi.nlm.nih.gov/pubmed/18183308
http://dx.doi.org/10.1371/journal.pone.0001430