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Schwann Cell Myelination Requires Timely and Precise Targeting of P(0) Protein

This report investigated mechanisms responsible for failed Schwann cell myelination in mice that overexpress P(0) (P(0) (tg)), the major structural protein of PNS myelin. Quantitative ultrastructural immunocytochemistry established that P(0) protein was mistargeted to abaxonal, periaxonal, and mesax...

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Detalles Bibliográficos
Autores principales: Yin, X., Kidd, G.J., Wrabetz, L., Feltri, M.L., Messing, A., Trapp, B.D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174550/
https://www.ncbi.nlm.nih.gov/pubmed/10704450